Searchable abstracts of presentations at key conferences in endocrinology

ea0005oc4 | Reproduction and Development | BES2003

Early developmental indices of placental growth restriction in the overfed adolescent sheep

Lea R , Hannah L , Redmer D , Fowler P , Murray J , Aitken R , Milne J , Wallace J

Introduction: Overfeeding adolescent ewes with singleton pregnancies results in reduced placental size and low lamb birth weight at term. We have investigated if reduced placental size is associated with altered placental cell proliferation and apoptosis at day 80 of pregnancy (peak placental growth period). Methods: Singleton pregnancies to a single sire were established by embryo transfer to adolescent recipient dams. Pregnant ewes were offered high (H, n = 14) or moderate (...